Spinach Chicken Casserole with Cream Cheese and Mozzarella

Looking for a comforting and delicious meal that’s easy to prepare and packed with flavor? This Spinach Chicken Casserole with Cream Cheese and Mozzarella is the perfect solution. Tender chicken breasts are baked to perfection, then topped with a creamy spinach mixture that includes cream cheese, sour cream, and a blend of mozzarella and Parmesan cheeses. The result is a savory, cheesy, and satisfying casserole that’s sure to please the whole family. Whether you’re serving it for a weeknight dinner or a special occasion, this dish is bound to be a hit!

This casserole combines rich flavors and creamy textures, creating a wholesome dish that brings together the heartiness of chicken, the goodness of spinach, and the melt-in-your-mouth comfort of cheese. The garlic and Italian seasoning add depth to the dish, making every bite irresistible. Best of all, this casserole is simple to prepare, requiring only a few ingredients and minimal effort. It’s a meal that feels indulgent while still being full of nourishing ingredients.

Why You’ll Love This Spinach Chicken Casserole with Cream Cheese and Mozzarella

This Spinach Chicken Casserole is not only delicious but also incredibly easy to make. It’s a one-pan dish that combines protein-rich chicken, vitamin-packed spinach, and a creamy, cheesy topping that’s the perfect balance of flavors. The richness of cream cheese and mozzarella perfectly complements the savory chicken, while the spinach adds a fresh, earthy flavor that cuts through the creaminess. Plus, the dish is versatile, so you can serve it alongside rice, quinoa, or even a simple green salad for a complete meal. It’s a great option for busy weeknights or when you’re entertaining guests!

Ingredients

For the Chicken:

• Boneless, skinless chicken breasts
• Salt
• Black pepper
• Garlic powder
• Onion powder
• Olive oil

For the Creamy Spinach Topping:

• Cream cheese, softened
• Sour cream (or Greek yogurt)
• Garlic, minced
• Italian seasoning
• Red pepper flakes (optional)
• Fresh spinach, chopped
• Shredded mozzarella cheese
• Grated Parmesan cheese

Variations

• Add More Veggies: Feel free to add more vegetables to the casserole, such as mushrooms, bell peppers, or zucchini, for added texture and flavor.
• Swap the Cheese: If you prefer a different cheese, you can substitute the mozzarella with provolone, cheddar, or a blend of cheeses that melt well.
• Low-Carb Option: For a lower-carb version, you can omit the sour cream and use full-fat Greek yogurt, or swap the chicken breasts for chicken thighs for a more flavorful and moist option.
• Spicy Kick: Add a bit more red pepper flakes or some diced jalapeños to the topping for extra heat.

How to Make the Spinach Chicken Casserole with Cream Cheese and Mozzarella

Step 1: Prepare the Chicken

Preheat your oven to 375°F (190°C). Season the boneless, skinless chicken breasts with salt, black pepper, garlic powder, and onion powder. Heat the olive oil in a large oven-safe skillet over medium-high heat. Add the chicken breasts and cook for about 4-5 minutes on each side, until the chicken is golden brown. Remove the chicken from the skillet and set it aside.

Step 2: Make the Creamy Spinach Topping

In the same skillet, add the minced garlic and sauté for about 1 minute until fragrant. Add the chopped spinach and cook until wilted, about 2-3 minutes. Reduce the heat to low and add the softened cream cheese, sour cream (or Greek yogurt), Italian seasoning, and red pepper flakes (if using). Stir everything together until the mixture is smooth and creamy. Add the shredded mozzarella cheese and grated Parmesan cheese, stirring until the cheese is melted and well combined.

Step 3: Assemble the Casserole

Return the chicken breasts to the skillet, spooning the creamy spinach mixture over the top of the chicken. Spread it evenly so that the chicken is fully covered. Place the skillet in the preheated oven and bake for 20-25 minutes, or until the chicken is cooked through and the cheese is bubbling and golden.

Step 4: Serve and Enjoy

Once the casserole is done, remove it from the oven and allow it to rest for a few minutes before serving. You can serve the casserole as-is or alongside your favorite side dish like rice, mashed potatoes, or a salad.

Tips for Making the Spinach Chicken Casserole with Cream Cheese and Mozzarella

• Don’t Overcook the Chicken: Be careful not to overcook the chicken, as it can become dry. If you have a meat thermometer, cook the chicken until it reaches an internal temperature of 165°F (75°C).
• Use Fresh Spinach: Fresh spinach will give the casserole a better flavor and texture than frozen spinach. Make sure to chop it finely so it mixes well with the creamy topping.
• Make It in Advance: If you want to prepare this casserole ahead of time, you can assemble everything up to the point of baking. Cover and refrigerate the casserole for up to 24 hours, then bake as instructed when you’re ready to serve.
• Add More Cheese: If you love cheese, feel free to add an extra layer of shredded mozzarella or even a sprinkle of Parmesan on top for an extra cheesy finish.

How to Serve

This Spinach Chicken Casserole is a perfect main dish, and it pairs wonderfully with sides like roasted vegetables, rice, quinoa, or a crisp green salad. For a lighter meal, serve it with steamed broccoli or a fresh cucumber salad. You can also enjoy it with a side of garlic bread or dinner rolls to soak up the creamy sauce.

Make Ahead and Storage

Storing Leftovers

Store any leftover casserole in an airtight container in the refrigerator for up to 3-4 days. Reheat in the microwave or in the oven until warmed through. If reheating in the oven, cover with foil to prevent the top from becoming too dry.

Freezing

This casserole can be frozen before or after baking. To freeze before baking, assemble the casserole, cover it tightly with plastic wrap and aluminum foil, and freeze for up to 3 months. When ready to bake, thaw the casserole in the refrigerator overnight and bake as directed. To freeze after baking, let the casserole cool completely, then wrap it tightly and freeze for up to 3 months.

Reheating

To reheat a frozen casserole, place it in the oven at 350°F (175°C) for 25-30 minutes, or until hot. If reheating from the refrigerator, bake at 350°F (175°C) for 15-20 minutes until warmed through.

FAQs

1. Can I use chicken thighs instead of chicken breasts?

Yes, chicken thighs are a great option for this casserole as they are more flavorful and tend to stay moist. Just adjust the cooking time accordingly.

2. Can I make this casserole without sour cream?

Yes, you can substitute sour cream with Greek yogurt or even mayonnaise for a different flavor. Both options will give the casserole a creamy texture.

3. Can I use frozen spinach instead of fresh?

While fresh spinach is recommended for the best texture, you can use frozen spinach if needed. Be sure to thaw and drain the spinach thoroughly to remove excess water.

4. Can I make this recipe in advance?

Yes, you can prepare the casserole ahead of time. Assemble it, cover it with plastic wrap or foil, and store it in the refrigerator until you’re ready to bake.

5. Can I add more vegetables to the casserole?

Absolutely! Feel free to add other vegetables like mushrooms, bell peppers, or zucchini to the creamy spinach mixture for extra flavor and nutrition.

6. Is this casserole gluten-free?

Yes, this casserole is naturally gluten-free as long as you use gluten-free ingredients, like gluten-free sour cream and cheese.

7. Can I use a different type of cheese?

Yes, you can substitute the mozzarella and Parmesan cheeses with other cheeses that melt well, such as provolone, gouda, or cheddar.

8. How can I make this recipe spicier?

You can add extra red pepper flakes or some chopped jalapeños to the creamy spinach topping for more heat.

9. Can I prepare the chicken in a slow cooker?

Yes, you can cook the chicken in a slow cooker and then top it with the spinach and cheese mixture before serving. Cook the chicken on low for 6-7 hours or high for 3-4 hours, then add the creamy spinach topping and cheese during the last 20-30 minutes of cooking.

10. How do I know when the chicken is fully cooked?

The internal temperature of the chicken should reach 165°F (75°C) to be fully cooked. Use a meat thermometer to check the temperature at the thickest part of the chicken breast.

Conclusion

This Spinach Chicken Casserole with Cream Cheese and Mozzarella is the ultimate comfort food. With its creamy spinach topping and perfectly baked chicken, it’s a dish that everyone will love. Whether you’re making it for a quick weeknight dinner or for a special gathering, this casserole is sure to impress. Easy to prepare and full of flavor, it’s a meal that’s both nourishing and indulgent.

Related Posts:

• Loaded Potato Ranch Chicken Casserole
• Cabbage Casserole Recipe
• Meatballs Parmesan Casserole

Print